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When she joined the SRDI, she had green eyes and short black hair that reaches to the top of her neck. A chain was wrapped around her head and hung on the left side of her face. A small tuft of hair hung from the bottom of the chain. She wore large square-rimmed spectacles and the standard Shinigami Shihakushō under a white lab coat. A hundred years later, the chain around her head is gone. She has a small chain hanging on either side of her head with a small tuft of hair suspended from each of them. Her hakama no longer extends below her thigh-length lab coat.
While she was working in one of the SRDI's labs, the reiatsu of members of the Ninth Division disappeared. Urahara came rushing into the lab and asked where Hiyori Sarugaki was. She told him that Hiyori had already left for the Ninth Division's location.
Soul Society arc
When Rukia Kuchiki is arrested in the Human World, she brings Rukia's Gigai to the lab as requested. When one of the other researchers asks who made the Gigai, she suggests that it ought to have been Akon, but notes that he does not seem like someone who would make that kind of Gigai. As they study it, Hiyosu and Akon look startled. She asks what it is and Akon tells her the Gigai was not made by anyone that is still in Soul Society.